Long Working Hours and Cardiovascular Disease

A Meta-Analysis of Epidemiologic Studies
Objective: To conduct a meta-analysis from published studies to evaluate the relationship between long working hours and the risk of cardiovascular disease (CVD).
Methods: Among a total of 341 published studies found from publicly accessible databases, five cohort studies and six case–control studies were analyzed for the study.
Results: Statistically significant heterogeneity has been observed (P = 0.037). The effect of longer working hours was significantly associated with the risk of CVD in the random-effects model of all 11 studies (odds ratio, 1.37; 95% confidence interval, 1.11 to 1.70). On the basis of meta-regression analysis, the result was not affected by the mean age, region, or the study year. The P value using Eager test was 0.701 suggesting this analysis was unlikely to have any publication bias.
Conclusions: These findings provide evidence of increased CVD with long working hours.

Source : Kang, Mo-Yeol MD; Park, Hyunseung MD; Seo, Jeong-Cheol MD; Kim, Donghoon MD; Lim, Youn-Hee PhD; Lim, Sinye MD, PhD; Cho, Soo-Hun MD, PhD; Hong, Yun-Chul MD, PhD. Journal of Occupational & Environmental Medicine: May 2012 - Volume 54 - Issue 5 - p 532–537.

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