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The impact of night shift work on breast cancer
Results from the Burden of Occupational Cancer in Canada Study Background: We estimated the proportion and number of female breast cancer cases in Canada attributable to night shift work, a probable cause of breast cancer. Methods: Levin's equation was used to calculate population attributable fractions (PAFs) among Canadian women who ever worked night/rotating shifts from 1961 to 2000, accounting for labor turnover and survival to the year 2011. The calculated PAFs were applied to 2011 Canadian breast cancer incidence statistics to obtain the number of attributable cases. Results: Approximately...
Night Shift Work Increases the Risks of Multiple Primary Cancers in Women
A Systematic Review and Meta-analysis of 61 Articles A growing number of studies have examined associations between night shift work and the risks of common cancers among women, with varying conclusions. We did a meta-analysis to identify whether long-term night shift work increased the risks of common cancers in women. We enrolled 61 articles involving 114,628 cases and 3,909,152 participants from Europe, North America, Asia, and Australia. Risk estimates were performed with a random-effect model or a fixed-effect model. Subgroup analyses and meta-regression analyses about breast cancer were conducted...
Night Shift Work Increases the Risks of Multiple Primary Cancers in Women
A Systematic Review and Meta-analysis of 61 Articles A growing number of studies have examined associations between night shift work and the risks of common cancers among women, with varying conclusions. We did a meta-analysis to identify whether long-term night shift work increased the risks of common cancers in women. We enrolled 61 articles involving 114,628 cases and 3,909,152 participants from Europe, North America, Asia, and Australia. Risk estimates were performed with a random-effect model or a fixed-effect model. Subgroup analyses and meta-regression analyses about breast cancer were conducted...
Outdoor Light at Night and Breast Cancer Incidence in the Nurses’ Health Study II
Background: Animal and epidemiologic studies suggest that exposure to light at night (LAN) may disrupt circadian patterns and decrease nocturnal secretion of melatonin, which may disturb estrogen regulation, leading to increased breast cancer risk.Objectives: We examined the association between residential outdoor LAN and breast cancer incidence using data from the nationwide U.S.-based Nurses' Health Study II cohort.Methods:We followed 109,672 women from 1989 through 2013. Cumulative LAN exposure was estimated using time-varying satellite data for a composite of persistent nighttime illumination...
Breast cancer link to shiftwork confirmed
Nearly 2,000 women contract breast cancer every year in the UK because they work night shifts, according to a new report. The figure, published by the Health and Safety Executive (HSE), is based on 2005 data and attributes 1,969 new cases of breast cancer and 555 deaths from the disease that year to shiftwork. It says: 'The estimate of nearly 2,000 breast cancer registrations due to shiftwork in our study is 54 per cent of all female occupationally-related cancer registrations.' Professor Andrew Watterson, head of occupational health research at Stirling University, urged HSE last year...

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