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Associations Between Age, Psychosocial Work Conditions, Occupational Well-Being, and Telomere Length in Geriatric Care Professionals
A Mixed-Methods Study Objective: We identified associations between age, psychosocial work characteristics, occupational well-being, and—as a measure of biological age—leukocyte telomere length in geriatric care professionals. Methods: This is a multisource study of self-reports on psychosocial work characteristics, standardized physician's evaluations of health, and relative telomere length measures of peripheral blood leukocytes. We included 141 geriatric care professionals. Telomere length was assessed by an improved polymerase chain reaction (PCR)-based method. Results: Increased...
Outdoor Light at Night and Breast Cancer Incidence in the Nurses’ Health Study II
Background: Animal and epidemiologic studies suggest that exposure to light at night (LAN) may disrupt circadian patterns and decrease nocturnal secretion of melatonin, which may disturb estrogen regulation, leading to increased breast cancer risk.Objectives: We examined the association between residential outdoor LAN and breast cancer incidence using data from the nationwide U.S.-based Nurses' Health Study II cohort.Methods:We followed 109,672 women from 1989 through 2013. Cumulative LAN exposure was estimated using time-varying satellite data for a composite of persistent nighttime illumination...
Does influence at work modify the relation between high occupational physical activity and risk of heart disease in women?
Purpose: To investigate whether influence at work modifies the association between demanding and strenuous occupational physical activity (OPA) and risk of ischaemic heart disease (IHD). Methods: A sample of 12,093 nurses aged 45–64 years from the Danish Nurse Cohort Study was followed for 20.6 years by individual linkage to incident IHD in the Danish National Patient Registry. Information on OPA, influence at work, other occupational factors and known risk factors for IHD was collected by self-report in 1993. Results: During follow-up 869 nurses were hospitalised with incident IHD. Nurses...
Night shift work and incidence of diabetes in the Danish Nurse Cohort
Objectives: Night shift work has been associated with poor sleep, weight gain, metabolic syndrome, which are recognised risk factor for diabetes. However, only a few studies have examined the effect of shift work on diabetes risk. Here, we study the association between shift work and incidence of diabetes in Danish nurses. Methods: We used the Danish Nurse Cohort with 28 731 participating female nurses recruited in 1993 (19 898) or 1999 (8833), when self-reported baseline information on diabetes prevalence, lifestyle and working time were collected, and followed them in the Danish Diabetes Register...
Reasons Why Physicians and Advanced Practice Clinicians Work While Sick
A Mixed-Methods Analysis Importance: When clinicians work with symptoms of infection, they can put patients and colleagues at risk. Little is known about the reasons why attending physicians and advanced practice clinicians (APCs) work while sick. Objective: To identify a comprehensive understanding of the reasons why attending physicians and APCs work while sick. Design, Setting, and Participants: We performed a mixed-methods analysis of a cross-sectional, anonymous survey administered from January 15 through March 20, 2014, in a large children's hospital in Philadelphia, Pennsylvania. Data...
Physical Capacity and Risk for Long-Term Sickness Absence
A Prospective Cohort Study Among 8664 Female Health Care Workers Objective: To assess the prospective associations between self-reported physical capacity and risk of long-term sickness absence among female health care workers. Methods: Female health care workers answered a questionnaire about physical capacity and were followed in a national register of sickness absence lasting for two or more consecutive weeks during 1-year follow-up. Using Cox regression hazard ratio analyses adjusted for age, smoking, body mass index, physical workload, job seniority, psychosocial work conditions, and previous...
General self-efficacy and the effect of hospital workplace violence on doctors' stress and job satisfaction in China
OBJECTIVES: This study aims at exploring associations of general self-efficacy (GSE), workplace violence and doctors' work-related attitudes. MATERIAL AND METHODS: In this study a cross-sectional survey design was applied. Questionnaires were administrated to 758 doctors working in 9 hospitals of Zhengzhou, Henan province, China, between June and October 2010. General information on age, gender, and years of working was collected, and the doctors' experience and witnessing workplace violence, job satisfaction, job initiative, occupational stress as well as GSE were measured. General linear...
Circadian gene expression in peripheral blood leukocytes of rotating night shift nurses
Objective : It has been hypothesized that the underlying mechanism of elevated breast cancer risk among long-term, night-working women involves circadian genes expression alteration caused by exposure to light at night and/or irregular work hours. The aim of the present study was to determine the effect of rotating night shift work on expression of selected core circadian genes. Methods : The cross-sectional study was conducted on 184 matched nurses and midwives, who currently work either day or rotating night shifts, to determine the effect of irregular work at night on circadian gene expression...
Bullying at work and onset of a major depressive episode among Danish female eldercare workers
Objective The aim of this study was to analyze whether exposure to workplace bullying among 5701 female employees in the Danish eldercare sector increases the risk of onset of a major depressive episode (MDE). Methods Participants received questionnaires in 2004–2005 and again in 2006–2007. MDE was assessed with the Major Depression Inventory. We examined baseline bullying as a predictor of onset of MDE at follow-up using multiple logistic regression. We further conducted a cross-sectional analysis at the time of follow-up among participants who at baseline were free of bullying, MDE...
Study finds that working shifts may increase the risk of developing diabetes in nurses
Examining the association between rotating shift work (≥3 nights/month plus days and evenings) and Type 2 diabetes among 177,000 female nurses aged 25–67 (the Nurses' Health Study), this large-scale study revealed a graded association between the duration of working life the nurses had been engaged in shift work and risk of developing Type 2 Diabetes. Compared with women who reported no shift work, participants with 1–2 years of shift work had a 5% excess risk of T2D, rising to 20% after 3–9 years, 40% after 10–19 years, and almost 60% for ≥20 years. These data...

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